The eagerly-awaited clash which brings Stuart Pearce's team to Hillsborough will see the former England full-back match up with his old Nottingham Forest team-mate Brian Laws.
Ironically enough, Pearce locked horns with Laws last season as City beat Scunthorpe in a third-round encounter.
Sheffield United play Swansea City at Bramall Lane on the Saturday so South Yorkshire Police would not have wanted both Sheffield teams playing on the same day.
Meanwhile, Graham Coughlan's late goal gave The Owls a 1-1 draw against Walsall reserves yesterday afternoon.