Sheffield Wednesday make their first ever trip to the Globe Arena on Sunday afternoon as they look to avoid a cup upset in front of the ESPN TV cameras.
Gary Megson will have to do without the services of loan pair Ben Marshall and Stephen Bywater as their parent clubs have prevented them from playing for the Owls in the F.A. Cup.
Jermaine Johnson is likely to replace Marshall and Richard O’Donnell could come in for Bywater between the sticks.
The Owls will also be without Liam Palmer as he is away on international duty with Scotland Under 21’s but top scorer Gary Madine is available for selection having served a suspension.
The home side have fitness concerns over defenders Will Haining and Lawrie Wilson and former Doncaster Rovers striker Jason Price. All 3 were forced off with injuries during the victory against Gillingham a fortnight ago and they all missed last weekends match at Plymouthas a result.
This will be the first ever meeting between the two sides with both coming into the match in decent form. Morecambe are unbeaten in their last five matches and currently occupy a play-off place in League Two though their overall form has been better away than it has been at home.
Wednesday have lost just one of their last nine matches but in contrast to their hosts the Owls have been far more consistent at home than they have been on their travels.